You are a police detective given the job of outsmarting and catching "The Boss" in his part of town.
Skid Row Adventure appeared in The Cuthbert Chronicle (Vol. 1, No. 4), which was Microdeal's own preview/review magazine. Anyone who did not want to type in the game could instead buy it direct from Microdeal's mail order arm (Micromail).
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The location descriptions contain American spellings so it is likely that the game was originally written for the CoCo and may pre-date the Microdeal copyright year (1985) that appears in the listing.